Acetal phosphatidic acids: novel platelet aggregating agents
نویسندگان
چکیده
منابع مشابه
Novel agents for anti-platelet therapy
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We would like to arrive at a single coherent pair of credences in X and X. Perhaps we wish to use these to set our own credences; or perhaps we wish to publish them in a report of the WHO as the collective view of expert epidemiologists; or perhaps we wish to use them in a decision-making process to determine how medical research funding should be allocated in 2018. Given their expertise, we wo...
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Chibnall and Channon, investigating the cytoplasma of cabbage and spinach leaves (I), isolated a mixture of substances which resembled monophosphatides in their structure and composition, but mere virtually free of nitrogenous bases. The main constituents were identified as the calcium, magnesium, and potassium salts of phosphoric acid esters of diglycerides. These compounds, constituting a new...
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The synthesis of novel acetal thia-cage compounds has been accomplished by the direct substitution for the oxygen atom by the sulfur atom in the reaction of the acetal groups of oxa-cages with Lawesson reagent (LR). Reaction of the tetraoxa-cage compound 2 with LR in dichloromethane at 25 degrees C sequentially gave the monothia-, dithia-, trithia-, and tetrathia-cage compounds 3, 6, 7, and 9. ...
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The ;swirling' seen when platelet-rich plasma is stirred is caused by the average asymmetry of the platelets and a technique for recording the swirling is reported. After the addition of adenosine diphosphate, 5-hydroxytryptamine, thrombin, and collagen, platelets become rounded and more symmetrical immediately before they become sticky. Monoiodo-acetate and adenosine prevent both the change in...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 1983
ISSN: 0007-1188
DOI: 10.1111/j.1476-5381.1983.tb10508.x